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I am a research fellow and team leader in the Lee Cronin research group at the University of Glasgow, where my team specializes in AI-driven chemistry automation, robotic platforms, and autonomous experimentation. I oversee team performance, set objectives, and supervise individual projects spanning hardware development to machine learning implementation. Over the years, I have developed expertise across multiple disciplines through experience at leading institutions including Oxford, ETH Zurich, and Glasgow. I started my scientific career as an organic chemist, progressed through physical-organic chemistry, and eventually transitioned to autonomous chemistry and robotics. My current work integrates large language models with chemical robots, computer vision for experiment monitoring, and closed-loop optimization algorithms. I have co-authored 28 scientific publications (26 peer-reviewed papers) and one patent.

Basics

Name Michael Jirasek
Label Research Fellow & Team Leader in AI-Driven Chemistry Automation
Email jirasekphd@gmail.com
Url https://www.michaeljirasek.com/

Work

  • 2022.01 - Present

    Glasgow, United Kingdom

    Research Fellow & Team Leader
    University of Glasgow
    Leading a diverse team of 9 researchers and graduate students in AI-driven chemistry automation. Implementing state-of-the-art large language models (LLMs) in automated chemistry laboratories, creating self-training robotic platforms for novel chemistry discoveries.
    • Leading and managing a diverse team of 9 researchers and graduate students
    • Implementing state-of-the-art large language models (LLMs) in automated chemistry laboratory
    • Designing and building chemical robotic prototypes using CAD software
    • Programming microcontroller firmware (Arduino and ESP32) and Python control software
    • Developing fully autonomous robotic platforms for chemical reactions and NMR analysis
    • Securing $1.25 million grant from the Sloan Foundation
    • Simulating 100,000s of IR, NMR and MS spectra for theoretical studies
    • Conducting high-throughput experiments on automated platforms
  • 2021.01 - 2021.12

    Zurich, Switzerland

    Postdoctoral Research Assistant
    ETH Zurich
    Developed novel soft materials by synthesizing collagen-like peptides combined with metals, analyzing their structure through transmission electron microscopy and XRD. Supervised master students and designed research projects.
    • Synthesising modified amino acids and peptides using SSPS
    • Fabricating large supramolecular assemblies and confirming structure with TEM
    • Designing bio-compatible porous peptide-based metal-organic frameworks
    • Supervising master students and devising research objectives
  • 2020.01 - 2020.12

    Oxford, United Kingdom

    Postdoctoral Research Assistant
    University of Oxford
    Developed MATLAB software to process NMR data from published literature during COVID lockdown. Conducted quantum chemical studies on molecular flexibility and aromaticity with findings published in top peer-reviewed journals.
    • Conceiving and developing original MATLAB software for predicting ring currents
    • Parsing NMR data from literature and interpreting using custom software
    • Computationally (DFT) and experimentally (NMR) studying aromaticity and ring-currents
  • 2010.09 - 2014.09

    Prague, Czech Republic

    Research Technician
    Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences
    Synthesized a library of over 200 novel azonia-helicenes and their full characterization as potential drug candidates for affecting telomerase activity. Screened for racemic conglomerate crystals using advanced techniques.
    • Synthesizing library of over 200 novel azonia-helicenes
    • Full characterization as potential drug candidates for telomerase activity
    • Screening for racemic conglomerate crystals by detecting second-harmonic generation and XRD
    • Organic compound synthesis for biological testing

Education

  • 2016.10 - 2020.02

    Oxford, United Kingdom

    PhD
    University of Oxford
    Physical Organic Chemistry
    • Graduate NMR course
    • Graduate Mass Spectrometry course
    • Communication Skills
  • 2014.09 - 2015.08

    Zurich, Switzerland

    Research Internship (Erasmus)
    ETH Zurich
    Organic Chemistry
    • Advanced Methods and Strategies in Synthesis
    • Organic Synthesis: Methods and Strategies
    • Computer-Assisted Drug Design
    • Functional Inorganics
  • 2013.09 - 2016.05

    Prague, Czech Republic

    MSc
    University of Chemistry and Technology
    Organic Chemistry
    • Organic Synthesis
    • Retrosynthesis
    • Reaction Mechanisms
    • Chemical Calculations
    • Organic Chemistry of Selected Elements
    • Coordination Chemistry
    • Metal-Organic Chemistry
    • Supramolecular Chemistry
    • Physical-Organic Chemistry
    • Organic Technology
  • 2010.09 - 2013.05

    Prague, Czech Republic

    BSc
    University of Chemistry and Technology
    Chemistry
    • Mathematics
    • Physics
    • Chemical Engineering
    • Physical Chemistry
    • Analytical Chemistry
    • General and Inorganic Chemistry
    • Organic Chemistry
    • Biochemistry

Skills

Programming & Software
Python (4+ years daily use)
MATLAB
TensorFlow & PyTorch
OpenAI & Claude API
MongoDB
Git repositories
Arduino & ESP32 firmware
Hardware & Robotics
CAD software (Onshape, AutoCAD)
3D printing (Stratasys J55, Origin, Prusa, Ultimaker, Bambu)
Laser cutting & CNC machining
Raspberry Pi & camera systems
Stepper motor control
I2C protocol
Microcontroller programming
Chemistry & Spectroscopy
NMR (high field & low field)
Mass spectrometry (MALDI, ESI, EI, LC-MS, MS/MS)
2D-IR, TRIR, Kerr gated Raman
UV-vis, CD, IR spectroscopy
Electrochemistry
Organic synthesis
Working under inert atmosphere
Computational Chemistry
Quantum-chemical calculations (NICS, AICD)
DFT calculations
Molecular modelling
AutoDock Vina
Chemoinformatics
Data Science & AI
Machine learning
Neural network architectures
Computer vision (OpenCV)
Data visualization (Plotly, Dash)
Pandas, NumPy, RDKit
Principal component analysis

Languages

English
Fluent
Czech
Native
German
Basic

Interests

Chemistry Automation
Hardware design in CAD
Writing firmware for microcontrollers
Robotic platform development
Autonomous discovery systems
AI & Machine Learning
Large language models
Computer vision
Spectroscopic data interpretation
Closed-loop optimization

Awards

  • 2019
    Poster Prize
    18th International Symposium on Novel Aromatic Compounds (ISNA-18), Sapporo, Japan
  • 2019
    Poster Prize
    Artemis, Octopus and ULTRA User Meeting, Oxford
  • 2013
    Best Oral Contribution
    13th Interdisciplinary Session of Young Biologist, Biochemists and Chemists